Focused on the research and development and production of resin materials and resin end products - Hebei Lijiang
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AboutHebei Lijiang Biotechnology Co., Ltd. is a new material manufacturer specializing in the production of functional special ion exchange resins and disposable blood perfusion devices. It is a modern high-tech enterprise integrating the research and development, production, sales, and service of resin materials and resin end products. The company was established in April 2014 with a registered capital of 52 million yuan. It plans to cover an area of 267 acres and is located in the High-tech Industrial Park of Weixian County, Hebei Province—New Material Demonstration Park. The total investment is 510 million yuan. It is a council member unit of the Ion Exchange Resin Branch of the China Membrane Industry Association.
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Product
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BlogsThe company will focus on the high-end market, with the purpose of serving society, solidly carrying out technological innovation and product promotion, continuously improving the development and expansion of ion exchange resin products in emerging application fields, thereby promoting the upgrading and development of related industries.
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Company AlbumThe current phase of construction has been fully completed and put into operation, featuring a comprehensive workshop with 42 production lines for functional ion exchange resins with an annual output of 16,800 tons and a production capacity of 30,000 tons, a wastewater treatment plant with an annual treatment capacity of 403,000 tons, and a workshop producing 5,000 tons of medical-grade magnesium sulfate annually. Trial production began in July 2016, with official production starting in January 2017.
Application of macroporous adsorption resin
Release Time:
2014-09-24
Due to the composition and structural characteristics of macroporous resins, which combine adsorption and selective separation, they possess multiple functions for separation and purification. They have been widely used in environmental protection, metallurgical industry, chemical industry, pharmaceutical and medical sectors. They are especially suitable for the separation and purification of biochemical products, natural products, drug preparation, organic compound separation, chemical reaction catalysts, carriers, and other fields. Macroporous adsorption resins have broad applications in the treatment of industrial wastewater and waste liquids. For example, they exhibit excellent adsorption, recovery, and purification effects on organic substances such as benzene, nitrobenzene, chlorobenzene, fluorobenzene, phenol, nitrophenol, aminophenol, bisphenol A, p-cresol, naphthol, aniline, o-phenylenediamine, p-phenylenediamine, salicylic acid, and naphthalenesulfonic acid contained in wastewater. They have strong adaptability to the concentration of harmful substances in waste liquids and can achieve compliance in a single treatment. This enables the recovery and reuse of harmful substances in industrial production, turning harm into benefit and waste into treasure.
The application of macroporous adsorption resins in microbial pharmaceutical separation and purification is also increasing. Some compounds that are weak electrolytes or non-ionic, which could not be extracted by ion exchange methods in the past, can now be tried with macroporous adsorption resins, providing a new approach for compound separation and purification. Macroporous resins remain one of the most active branches in the field of reactive polymer technology. Practical applications show that they have greater adsorption capacity than other natural adsorbents (or gel-type resins), are easy to elute, have high mechanical strength, and strong anti-pollution ability. Especially, their pore size, porosity, specific surface area, polarity, and other properties can be artificially controlled and adjusted for any selection. Therefore, they have gradually replaced classic adsorbents such as activated carbon and Al2O3, supplemented the shortcomings of ion exchange resins, and provided important means for microbial pharmaceutical separation, extraction, concentration, and purification.
New Technology:
In recent years, due to the introduction of new macroporous adsorption resin technologies, the indicators of effective monomer components or certain monomer components in compound traditional Chinese medicines have been improved. It has advantages such as speed, efficiency, convenience, sensitivity, and good selectivity, thus developing rapidly and being widely applied.
1: Application of macroporous adsorption resins in the purification of effective components of traditional Chinese medicine: Macroporous adsorption resins are used for the separation of total paeoniflorin from white peony, stevioside, rosehip glycosides, total saponins of Panax notoginseng, total saponins of American ginseng, total saponins of Gynostemma pentaphyllum, glycyrrhizic acid, alkaloids from three-needle pine, paeonol, flavonoids from Ginkgo biloba leaves, total alkaloids from processed Aconitum kusnezoffii and Aconitum carmichaelii, uracil and uridine from thin-shelled Ganoderma lucidum, ligustrazine and ferulic acid.
2: Application of macroporous adsorption resins in compound preparations of traditional Chinese medicine: Zhang used D-type macroporous adsorption resin to determine the total saponins of Panax notoginseng and its preparation Guanxin Ning. Others treated Panax notoginseng royal jelly with D201 column to measure the content of Panax notoginseng saponins, achieving a recovery rate of 104.4%. Liu and others conducted internal control tests on compound capsules (containing 25 kinds of traditional Chinese medicines including Panax notoginseng) and effectively separated Panax notoginseng saponins using macroporous adsorption resin adsorption method, followed by TLC qualitative identification, resulting in good spot separation and reproducibility. Ren and others used D-type macroporous adsorption resin (Tianjin Bone Glue Factory) to purify total ginsenosides in Qixue injection and Shengmai injection. Hu and others used macroporous adsorption resin separation-colorimetric method to determine total ginsenosides in Shengmai injection, improving separation effect, reducing influencing factors, and achieving good reproducibility of sample content with an average recovery rate above 100.1%. Phenylethanoid glycosides are effective components of Cistanche; macroporous adsorption resin (AB/B type) has good separation performance for phenylethanoid glycosides. D101 type macroporous adsorption resin can purify astragaloside from Astragalus. Shou used low-polarity GDX104 macroporous adsorption resin to separate and purify paeoniflorin components in Shugan Zhitong tablets. Zhong used chitosan as a flocculant and resin M as an adsorbent to improve the production process of Guilu Bushen liquid. The new process reduced one concentration step compared to the original, and the costs of chitosan and resin M are lower than alcohol, shortening production cycle, reducing energy consumption, lowering production costs, and improving production efficiency. Wang and others used X5 macroporous adsorption resin produced by Nankai University to separate and purify icariin components in Guilu Bushen liquid. Samples treated with X5 adsorption resin effectively removed some impurities, achieving ideal separation effects in high-performance liquid chromatography.
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24-05-14 14:37:56
